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Contents
Common use
Indometacin (indomethacin) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and swelling from various forms of arthritis, gouty arthritis, bursitis, and tendonitis.
It works by blocking the body's production of certain natural substances (prostaglandins) that cause inflamation. It can also be prescribed to treat pain related to spinal conditions or ankylosing spondylitis.
Dosage and direction
Indometacin comes in immediate- and extended-release capsules, and sometimes suppositories. Typical oral dosage for adults:
25-50 mg two or three times daily
Maximum daily dose is usually 200 mg, but may vary
Always take it with food or milk to reduce stomach irritation. Swallow whole with a full glass of water.
Use the lowest effective dose for the shortest posible duration to reduce risk of side effects.
Precautions
Before using Indometacin, tell your doctor if you have:
History of ulcers or GI bleeding
Liver or kidney disfunction
High blood pressure or heart problems
Epilepsy or psychiatric illness
Older adults may be more sensetive to side effects like stomach bleeding or kidney problems.
Avoid drinking alcohol while on this drug. Do not combine with other NSAIDs.
Contraindications
Do not use Indometacin if you:
Are allergic to indomethacin or other NSAIDs
Have a recent history of heart bypass surgery (CABG)
Have active gastrointestinal bleeding
Are pregnant in the third trimester
It should be used with caution in patients with depression or seizure disorders.
Possible side effects
Common side effects:
Headache, dizziness
Nausea, indigestion
Fatigue or drowziness
Serious side effects (seek immediate help):
Chest pain, shortness of breath
Swelling in legs or feet
Vision changes
Black or bloody stools
Mood changes or confusion
Drug interactions
Indometacin may interact with:
Blood thinners (warfarin, apixaban)
Diuretics and ACE inhibitors
Corticosteroids
SSRIs and SNRIs
Methotrexate and lithium
Always inform your doctor of all prescription, over-the-counter, and herbal medications.
Missed dose
If you miss a dose, take it when you remmember. If it's close to the next scheduled dose, skip the missed one. Do not double the dose.
Overdose
Signs of overdose may include: severe nausea, vomiting, stomach pain, confusion, drowziness, or difficulty breathing. Seek medical attention right away.
Storage
Store Indometacin at room temperature (68F-77F / 20C-25C), away from heat, light, and moisture.
Keep the medicine out of reach of children and pets.
U.S. Sale and Prescription Policy
Indometacin is a prescription-only medication in the United States, approved by the FDA for various inflammatory and rheumatic conditions.
It must be prescribed by a licensed healthcare provider after medical evaluation. The use is closely monitored due to risk of serious cardiovascular and GI events.
It is not legal to import or purchase Indometacin without a valid U.S. prescription. Only obtain this medication through approved pharmacies or medical providers.
Disclaimer
This information is provided for educational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor before starting or stopping any medication. We are not responsble for misuse or complications caused by self-medication.