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Contents
Common use
Cafergot is a combination medication containing ergotamine tartrate and caffeine. It is used to treat migraines and cluster headaches by narrowing the widened blood vessels in the brain and decreasing inflammation.
Ergotamine affects blood flow, while caffeine improves its absorption and effectiveness.
This medicine is not for everyday headache prevention. It is typically used at the onset of migraine symptoms.
Dosage and direction
Cafergot is usually taken at the first sign of a migraine attack. The usual starting dose is 1-2 tablets, and you may take 1 tablet every 30 minutes as needed, not exceeding 6 tablets per attack or 10 per week.
Take it with a full glass of water. Lying down in a dark, quiet room can enhance the medicine's effect.
Do not exceed the recomended dose. Overuse can worsen headaches or cause rebound migraines.
Precautions
Before taking Cafergot, tell your doctor if you have:
High blood pressure
Liver or kidney disease
Circulation problems
Heart conditions or recent heart attack
Pregnancy or breastfeeding
Avoid using other migraine drugs within 24 hours of taking Cafergot. Smoking may increase the risk of side effects, especially vascular ones.
Contraindications
Do not use Cafergot if you:
Are allergic to ergot alkaloids or caffeine
Have peripheral vascular disease
Have severe hypertension
Are pregnant (can harm the fetus)
Are taking certain antifungals, antibiotics, or HIV meds
This medicine is not suitable for use in children.
Possible side effects
Common side effects:
Nausea or vomitting
Tingling or numbness in fingers or toes
Weakness or dizzyness
Serious effects (seek medical help):
Pain in chest or limbs
Cold or pale fingers and toes
Muscle pain in arms or legs
Blue-colored skin
Long-term overuse may lead to ergotism, a rare but dangerous condition causing severe blood flow problems.
Drug interactions
Avoid using Cafergot with:
Macrolide antibiotics (e.g., erythromycin)
HIV protease inhibitors
Triptans
Certain antifungal drugs (e.g., ketoconazole)
Beta-blockers
Always inform your doctor of any other meds, supplements, or herbal products you're using.
Missed dose
Cafergot is used as needed for migraines. If a dose is missed and you're still having symptoms, take it when remembered. Do not double doses to catch up.
Overdose
Symptoms of overdose include leg pain, cold hands and feet, drowsiness, confusion, and severe nausea.
Seek emergancy medical care right away if you suspect overdose.
Storage
Store Cafergot at room temperature (68F-77F or 20C-25C) in a dry place away from heat and sunlight. Keep out of reach of children.
U.S. Sale and Prescription Policy
Cafergot is a prescription-only medication in the United States. It is no longer widely available or commonly prescribed due to the introduction of newer migraine treatments with better safety profiles.
The FDA has not banned it, but it is limited in supply, and prescriptions are typically filled through specialty or compounding pharmacies.
A valid prescription from a licensed U.S. healthcare provider is required to purchase legally. Online purchases from foreign pharmacies may violate FDA importation rules and carry risk of conterfeit products.
Disclaimer
This information is educational and not a substitute for medical advice. Always consult a doctor or pharmacist before using any prescription medicine. We are not responsble for any adverse outcomes from incorrect usage.